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Targets Recommended: VEGFR

57

抑制剂 & 化合物

3

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化合物库

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Cat. No. Product Name
L1610 FDA 上市激酶抑制剂库

263 compounds
263种靶向激酶的上市药物集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选;
L1600 激酶抑制剂库

2720 compounds
2720 种激酶抑制剂/调节剂的独特集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选;

化合物库

FDA 上市激酶抑制剂库
Cat.No: L1610
Compounds: 263
激酶抑制剂库
Cat.No: L1600
Compounds: 2720
Cat. No. Product Name Target Signaling Pathways
T72924 VEGFR-3-IN-1

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
VEGFR-3-IN-1 是一种新型有效且具有选择性的 VEGFR3 抑制剂,其 IC50 为 110.4 nM。VEGFR-3-IN-1 具有抗肿瘤活性,可使 VEGFR3 信号通路失活,可抑制 VEGF-C 诱导人真皮淋巴管内皮细胞 (HDLEC)、MDA-MB-231 和 MDA-MB-436 细胞的增殖和迁移,并且能有效抑制乳腺癌的生长。
T2032 WHI-P180

Janex 3

EGFR; VEGFR; c-RET; CDK Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; JAK/STAT signaling; Tyrosine Kinase/Adaptors
WHI-P180 (Janex 3) 是 EGFR 和 Cdk2 抑制剂,IC50 分别为 4.0 和 1.0 μM。
T63112 VEGFR-IN-3

VEGFR-IN-3 (compound 3f) 是 VEGFR 抑制剂。VEGFR-IN-3 抑制 OVCAR-4 和 MDA-MB-468 癌细胞的生长,其 IC50值分别为 0.29 和 0.35 μM。VEGFR-IN-3 可用于癌症的研究。
T22432 SU5208

3-[(Thien-2-yl)methylene]-2-indolinone

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) 对血管内皮生长因子受体2具有抑制作用。
T4425 JK-P3

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
JK-P3 是广谱 VEGFR2抑制剂。它能够抑制 VEGF-A 刺激的 VEGFR2 激活和细胞内信号转导,也可阻碍内皮单层细胞迁移和血管生成,影响成纤维细胞生长因子受体激酶在体外的活性。它具有抗血管生成的作用。
T9473 4SC-203

FLT Angiogenesis; Tyrosine Kinase/Adaptors
4SC-203 是一种具有潜在的抗肿瘤活性的多激酶抑制剂。它对 FLT3/STK1、 FLT3 的突变形式以及 VEGFRs 具有选择性抑制作用。
T22431 SU5204

3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one

EGFR; VEGFR; HER Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one) 是酪氨酸激酶抑制剂,是 SU5025 的类似物,对 FLK-1 (VEGFR-2) 和 HER2 的IC50分别为 4 和 51.5 μM。
T1836 AZD2932

VEGFR; FLT; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
AZD2932是一种多靶点激酶抑制剂,细胞试验中能够抑制 VEGFR2 (IC50:8 nM),PDGFβ (IC50:4 nM),PDGFβ (IC50:7 nM) 和 PDGFβ (IC50:9 nM)。
T2638 Gandotinib

LY2784544

VEGFR; FGFR; FLT; JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
Gandotinib (LY2784544) 是一种JAK2抑制剂,IC50为 3 nM。它也抑制FLT3、FLT4、FGFR2、TYK2 和 TRKB,IC50分别为 4、25、32、44 和 95 nM。
T2054 Altiratinib

DCC-2701

VEGFR; Tie-2; FLT; Trk receptor; c-Met/HGFR Angiogenesis; Tyrosine Kinase/Adaptors
Altiratinib (DCC-2701) 是一种多靶点激酶抑制剂,能够抑制 MET (IC50:2.7 nM),TIE2 (IC50:8 nM),VEGFR2 (IC50:9.2 nM),FLT3 (IC50:9.3 nM),Trk1 (IC50:0.85 nM),Trk2 (IC50:4.6 nM) 和 Trk3 (IC50:0.83 nM)。
T0093L Sorafenib

索拉非尼,Bay 43-9006

Apoptosis; Raf; VEGFR; FLT; Ferroptosis; PDGFR; c-Kit; Autophagy Angiogenesis; Apoptosis; Autophagy; MAPK; Tyrosine Kinase/Adaptors
Sorafenib (Bay 43-9006) 是一种多激酶抑制剂,抑制 Raf-1、B-Raf、VEGFR2、VEGFR3VEGFR4、PDGFRβ、FLT3、c-Kit 等 (IC50=6/22/90/15/20/20/57/58 nM),具有口服活性。Sorafenib 具有抗肿瘤活性,可以诱导细胞自噬和凋亡,也可以激动铁死亡。
T2358 ENMD-2076

Apoptosis; VEGFR; FGFR; FLT; c-RET; PDGFR; Src; Aurora Kinase Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
ENMD2076是一种多靶点激酶抑制剂,抑制Aurora A、Flt3、KDR/VEGFR2、Flt4/VEGFR3、FGFR1、FGFR2、Src、PDGFRα的IC50值分别为1.86、14、58.2、15.9、92.7、70.8、20.2 and 56.4 nM。
T79588 hCA/VEGFR-2-IN-3

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
hCA/VEGFR-2-IN-3(compound 8j)是一种吲哚酮基苯磺酰胺类化合物,作为hCA IX/XII和VEGFR-2的双重抑制剂,在抗癌领域具有潜在应用。该化合物对VEGFR-2表现出显著的抑制活性(IC50=358 nM),并且与hCAs有较高的亲和力,具体活性为:Ki值分别为4.2 nM(hCA IX),22.9 nM(hCA II),25.1 nM(hCA I)和28.0 nM(hCA XII)。此外,hCA/VEGFR-2-IN-3还对过表达VEGFR-2的乳腺癌细胞显示出抗增殖效果。
T0093 Sorafenib tosylate

甲苯磺酸索拉非尼,Bay 43-9006

Apoptosis; Raf; VEGFR; FLT; Ferroptosis; PDGFR; c-Kit; Autophagy Angiogenesis; Apoptosis; Autophagy; MAPK; Tyrosine Kinase/Adaptors
Sorafenib tosylate (Bay 43-9006) 是一种口服活性Raf 抑制剂,也是铁死亡激动剂。它是多激酶抑制剂,对VEGFR2,VEGFR3,PDGFRβ,FLT3和c-Kit 的IC50分别为 90 nM,15 nM,20 nM,57 nM 和 58 nM。它诱导细胞自噬和凋亡,有抗肿瘤活性。
T8482 Ripretinib

DCC-2618,瑞普替尼

Apoptosis; VEGFR; FLT; PDGFR; c-Kit Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Ripretinib (DCC-2618) 是一种口服生物利用的,选择性 KIT 和 PDGFRA 开关控制抑制剂,具有抗肿瘤作用并诱导细胞凋亡。它专门针对 KIT 和 PDGFRA 的野生型和突变型并与之结合在其开关口袋结合位点,从而防止这些激酶从无活性构象转变为有活性构象,并使它们的野生型和突变体形式失活。
T4053 AST 487

NVP-AST 487

VEGFR; FLT; c-RET; Bcr-Abl; c-Kit Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
AST 487 (NVP-AST 487) 是 RET 激酶抑制剂 (IC50:880 nM),能够抑制 RET 自磷酸化,及下游效应器激活,也抑制 Flt-3 (IC50:520 nM)。
T79858 TIE-2/VEGFR-2 kinase-IN-3

TIE-2/VEGFR-2 kinase-IN-3,为苯并咪唑衍生物,具备高效的抑制作用于TIE-2与VEGFR-2受体酪氨酸激酶,其IC50值分别达到6.9 nM和3.5 nM。本化合物主要用于血管生成相关研究。
T7493 AG-13958

AG-013958,N-[2-氟-5-[[3-[(1E)-2-(2-吡啶基)乙烯基]-1H-吲唑-6-基]氨基]苯基]-1,3-二甲基-1H-吡唑-5-甲酰胺

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
AG-13958 (AG-013958) 是 VEGFR 酪氨酸激酶抑制剂,可用于年龄相关性黄斑变性 (AMD) 的脉络膜新生血管形成的研究。
T79009 VEGFR2-IN-3

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
VEGFR2-IN-3 (compound 385)为高效VEGFR2抑制剂。
T2586 Cabozantinib

卡博替尼,XL184,BMS-907351

Apoptosis; VEGFR; FLT; c-Met/HGFR; c-RET; TAM Receptor; c-Kit Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Cabozantinib (XL184) 是一种多靶点酪氨酸激酶受体抑制剂,可以抑制 VEGFR2、c-Met、Kit、Axl 和 Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM)。Cabozantinib 具有抗肿瘤和抗血管生成活性。
T4349 Sitravatinib

MG516,MGCD516

Discoidin Domain Receptor (DDR); VEGFR; FLT; Trk receptor; TAM Receptor; c-Kit; Ephrin Receptor Angiogenesis; Tyrosine Kinase/Adaptors
Sitravatinib (MGCD516) 是一种有口服活性的受体酪氨酸激酶抑制剂。它单独使用即具有有效的抗肿瘤功效,且通过促进抗肿瘤免疫微环境增强了 PD-1 阻断的活性。
T72713 PI3K/VEGFR2-IN-1

PI3K PI3K/Akt/mTOR signaling
PI3K/VEGFR2-IN-1是一种具有双重抑制效应的化合物,对PI3K和VEGFR2的IC50分别为2.21 μM和68 μM,能够诱导细胞凋亡(apoptosis),在癌症研究中应用。
T6479 Dovitinib lactate hydrate

Dovitinib (TKI258) Lactate,多韦替尼,Dovitinib Lactate,TKI258

VEGFR; FGFR; FLT; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Dovitinib lactate hydrate (TKI258) 是一种多靶点的酪氨酸激酶抑制剂,抑制 FLT3,c-Kit,FGFR1/3VEGFR1/2/3和 PDGFRα/β的 IC50值分别为 1,2,8/9,10/13/8,27/210 nM。
T7104 Dovitinib lactate

CHIR-258 lactate,多韦替尼乳酸盐,TKI-258 lactate

VEGFR; FGFR; FLT; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Dovitinib lactate (TKI-258 lactate) 是一种多靶点的酪氨酸激酶抑制剂,抑制FLT3,c-Kit,FGFR1/3VEGFR1/2/3和PDGFRα/β的IC50值分别为 1,2,8/9,10/13/8,27/210 nM。
T6289 Dovitinib

TKI258,多韦替尼,CHIR-258,度维替尼

VEGFR; FGFR; FLT; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Dovitinib (CHIR-258) 是一种口服有效的、多靶点的酪氨酸激酶 (RTK) 抑制剂,具有抗肿瘤作用。
T2514 Linifanib

利尼伐尼,ABT-869,RG3635,AL-39324

Apoptosis; c-Fms; VEGFR; FLT; CSF-1R; PDGFR; c-Kit; Autophagy Angiogenesis; Apoptosis; Autophagy; Tyrosine Kinase/Adaptors
Linifanib (AL-39324) 是一种高效口服的VEGFR 和PDGFR 家族多靶点抑制剂,具有显著的抗肿瘤活性。它对无关 RTKs、可溶性酪氨酸激酶或丝氨酸/苏氨酸激酶的活性要低得多。它是特异性 miR-10b 抑制剂,阻断miR-10b 的生物合成。
T5164 Cabozantinib hydrochloride

XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351,盐酸卡博替尼

VEGFR; FLT; c-Met/HGFR; TAM Receptor; c-Kit; ROR Angiogenesis; Metabolism; Tyrosine Kinase/Adaptors
Cabozantinib hydrochloride (XL184) 是一种有效的泛酪氨酸激酶抑制剂,可抑制 VEGFR2、c-Met、Kit、Axl 和 Flt4(IC50:0.035、1.3、4.6、7 和 6 nM)。
T6028 PF 477736

PF 00477736,PF-477736,PF-736,PF-00477736,PF477736

c-Fms; VEGFR; FGFR; FLT; c-RET; Chk; CDK; Src; Aurora Kinase Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
PF 477736 (PF-736,PF-00477736) 是一种特异性、有效且具有 ATP 竞争性的 Chk1 抑制剂,Ki 值为0.49 nM。它也是Chk2抑制剂,Ki 值为 47 nM。它还抑制VEGFR2、Fms、Yes、Aurora-A、FGFR3、Flt3和Ret。
T3691 (Rac)-SAR131675

SAR131675

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
(Rac)-SAR131675 是一种有效的、选择性的VEGFR3抑制剂,其IC50=23 nM。
T63505 Tivozanib hydrochloride hydrate

AV-951 hydrochloride hydrate,KRN951 hydrochloride hydrate

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
Tivozanib hydrochloride hydrate (AV-951 hydrochloride hydrate) 是一种具有口服活性、选择性和高效性的血管内皮生长因子受体 (VEGFR) 酪氨酸激酶抑制剂,抑制 VEGFR-1、VEGFR-2、VEGFR-3 ,可用于研究转移性肾细胞癌 (RCC)和乳腺癌等实体肿瘤疾病。
T8496 MAZ51

Apoptosis; VEGFR Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
MAZ51 是一种 VEGFR-3酪氨酸激酶的选择性抑制剂。它抑制 VEGF-C 诱导的 VEGFR-3 激活,而没有阻断 VEGF-C 介导的 VEGFR2 刺激。它阻止增殖并诱导多种肿瘤细胞凋亡,具有抗肿瘤活性。
T11153 EG00229

Others Others
EG00229 selectively inhibits VEGF-A binding to NRP1 b1 domain with an IC50 of 3 μM, but has no effect on VEGFA binding to VEGFR-1 and VEGFR-2. EG00229 is a neuropilin 1 (NRP1) receptor antagonist.
T3463 NVP-ACC789

ACC-789,ZK202650

VEGFR; PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
NVP-ACC789 (ZK202650) 是一种人VEGFR-1,VEGFR-2(鼠VEGFR-2),VEGFR-3 和 PDGFR-β 的抑制剂,它们的 IC50 值分别为 0.38,0.02 (0.23),0.18 和 1.4 μM。
T6036 Brivanib

BMS-540215,布立尼布

EGFR; VEGFR; FGFR; Autophagy Angiogenesis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Brivanib (BMS-540215) 是一种针对 VEGFR2 的 ATP 竞争性抑制剂,IC50 为 25 nM。它对 VEGFR-1 和 FGFR-1 具有中等效力,对 VEGFR2 的选择性是对 PDGFR-β 的 240 倍。
T16909 Sorafenib-d3

Sorafenib (D3),Bay 43-9006 (D3)

Raf; VEGFR Angiogenesis; MAPK; Tyrosine Kinase/Adaptors
Sorafenib-d3 (Bay 43-9006 (D3)) 是一种氘标记的 Sorafenib,Sorafenib 是一种多激酶抑制剂(对 Raf-1、B-Raf 和 VEGFR-3 的 IC50 分别为 6 nM、20 nM 和 22 nM)。
T2288 Motesanib

AMG 706,莫特塞尼,莫替沙尼

VEGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Motesanib (AMG 706) 是有效的、ATP 竞争性的 VEGFR1/2/3 的抑制剂,其IC50值为 2 nM/3 nM/6 nM,与对 Kit 的选择性相似,是 PDGFR 和 Ret 的 10 倍多。
T0263 Chloropyramine hydrochloride

Nilfan,盐酸氯吡胺,Alergosan,Halopyramine hydrochloride

FAK; VEGFR; Histamine Receptor Angiogenesis; Cytoskeletal Signaling; GPCR/G Protein; Immunology/Inflammation; Neuroscience; Tyrosine Kinase/Adaptors
Chloropyramine hydrochloride (Alergosan) 是一种组胺受体 H1 拮抗剂,可抑制VEGFR-3和FAK 的生化功能。
T14943 CGP60474

VEGFR; CDK; PKC Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
CGP60474 是一种高效的抗内毒素药物,抑制细胞周期蛋白依赖激酶(CDK) ,抑制 CDK1/B、CDK2/E、CDK2/a、CDK4/D、CDK5/p25、CDK7/H 和 CDK9/T 的IC50分别为 26、3、4、216、10、200 和 13 nM。它是选择性和 ATP 竞争性PKC 抑制剂。
T2456 Tivozanib

替沃扎尼,AV-951,KRN951

VEGFR; PDGFR; Ephrin Receptor Angiogenesis; Tyrosine Kinase/Adaptors
Tivozanib (KRN951) 是一种选择性的 VEGFR 1/2/3抑制剂,它们的 IC50值分别为0.21 nM、0.16 nM、0.24 nM。
T2500 Cediranib

AZD2171,NSC-732208,西地尼布

VEGFR; FLT; PDGFR; c-Kit; Autophagy Angiogenesis; Autophagy; Tyrosine Kinase/Adaptors
Cediranib (AZD2171) 是一种可口服的高选择性VEGFR2抑制剂,对Flt1、KDR、Flt4、PDGFRα、PDGFRβ和c-Kit 的IC50值分别为小于1、小于3、5、5、36和 2nM。
T0097L Pazopanib

帕唑帕尼,GW786034

VEGFR; FGFR; PDGFR; c-Kit; Autophagy Angiogenesis; Autophagy; Tyrosine Kinase/Adaptors
Pazopanib (GW786034) 是一种小分子抑制剂,可抑制多种具有潜在抗肿瘤活性的蛋白酪氨酸激酶。它抑制VEGFR1、VEGFR2、VEGFR3、PDGFRβ、c-Kit、FGFR1和c-Fms 的IC50分别为10、30、47、84、74、140和146 nM。
T2624 OSI-930

OSI 930,噻尔非尼

Apoptosis; c-Fms; Raf; VEGFR; FLT; CSF-1R; Src; c-Kit Angiogenesis; Apoptosis; MAPK; Tyrosine Kinase/Adaptors
OSI-930 是 Kit,KDR 和 CSF-1R (c-Fms)的口服选择性抑制剂,IC50分别为 80 nM,9 nM 和 15 nM。它具有抗肿瘤活性,靶向肿瘤中的癌细胞增殖和血管生成。它还适度抑制 Flt-1,c-Raf 和 Lck,并且对 PDGFRα/β,Flt-3和 Abl 具有较弱的抑制活性。
T2656 Fruquintinib

HMPL-013,呋喹替尼

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
Fruquintinib (HMPL-013) 是一种选择性的VEGFR 1/2/3抑制剂,它们的IC50值分别为33 nM、0.5 nM、35 nM。
T1656L Vandetanib Fumarate

HSDB 8198,Zactima,Caprelsa,ZD 6474,Vandetanib

Vandetanib Fumarate is an orally available tyrosine kinase inhibitor. Vandetanib Fumarate works by blocking RET (REarranged during Transfection), vascular endothelial growth factor receptor (VEGFR-2, VEGFR-3), and epidermal growth factor receptor and to a
T12791 (S)-3-Hydroxy Midostaurin

(S)-CGP52421

Others Others
(S)-3-Hydroxy Midostaurin is a potent inhibitor of kinases(IC50 of <400 nM for 13 kinases (VEGFR-2, TRK-A, FLT3, et)).
T77148 Pegdinetanib

Pegdinetanib (BMS-844203; CT-322) 是一种选择性 VEGFR-2(VEGFR) 抑制剂,对人和鼠 VEGFR-2 的 Kd 分别为 11 nM 和 250 nM,IC50分别为 16 nM 和 240 nM。Pegdinetanib 不与 VEGFR-1或 VEGFR-3结合。Pegdinetanib 具有抗肿瘤活性。
T74127 N-Desethyl Sunitinib hydrochloride

N-Desethyl Sunitinib (SU-12662) (hydrochloride) 是 Sunitinib 的代谢物。Sunitinib 是有效的,ATP 竞争的VEGFR,PDGFRβ和KIT 抑制剂,能够抑制VEGFR-1,VEGFR-2,VEGFR-3,PDGFRβ和 KIT 的活性,Ki 值分别为 2,9,17,8 和 4 nM。
T79495 VEGFR-2-IN-32

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
VEGFR-2-IN-32(Comp 3a)作为一种VEGFR-2的抑制剂,其IC50值为8.93 nM。该化合物对PC-3细胞表现出细胞毒性,IC50为1.22 μM,适用于前列腺癌研究。
T63870 Multi-kinase-IN-3

Multi-kinase-IN-3 (compound 2) 是血管激酶 (angiokinase) 的有效抑制剂,能够抑制 VEGFR-2 (IC50: 58.3 nM) 和 PDGFRβ (IC50: 55 nM)。
T12145 N-Desethyl Sunitinib

N-去乙基-舒尼替尼,SU-11662

VEGFR; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
N-Desethyl Sunitinib (SU-11662) 是 Sunitinib 的代谢物。其中 Sunitinib 是有效的以及ATP 竞争的VEGFR、PDGFRβ和KIT 抑制剂,能够抑制 VEGFR -1 (Ki:2 nM) 、VEGFR-2 (Ki:9 nM) 、VEGFR-3 (Ki:17 nM) 、PDGFRβ (Ki:8 nM) 、KIT (Ki:4 nM) 的活性。

化合物

VEGFR-3-IN-1
Cat.No: T72924
Synonym:
Target: VEGFR
WHI-P180
Cat.No: T2032
Synonym: Janex 3
Target: EGFR, VEGFR, c-RET, CDK
VEGFR-IN-3
Cat.No: T63112
Synonym:
Target:
SU5208
Cat.No: T22432
Synonym: 3-[(Thien-2-yl)methylene]-2-indolinone
Target: VEGFR
JK-P3
Cat.No: T4425
Synonym:
Target: VEGFR
4SC-203
Cat.No: T9473
Synonym:
Target: FLT
SU5204
Cat.No: T22431
Synonym: 3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one
Target: EGFR, VEGFR, HER
AZD2932
Cat.No: T1836
Synonym:
Target: VEGFR, FLT, PDGFR, c-Kit
Gandotinib
Cat.No: T2638
Synonym: LY2784544
Target: VEGFR, FGFR, FLT, JAK
Altiratinib
Cat.No: T2054
Synonym: DCC-2701
Target: VEGFR, Tie-2, FLT, Trk receptor, c-Met/HGFR
Sorafenib
Cat.No: T0093L
Synonym: 索拉非尼,Bay 43-9006
Target: Apoptosis, Raf, VEGFR, FLT, Ferroptosis, PDGFR, c-Kit, Autophagy
ENMD-2076
Cat.No: T2358
Synonym:
Target: Apoptosis, VEGFR, FGFR, FLT, c-RET, PDGFR, Src, Aurora Kinase
hCA/VEGFR-2-IN-3
Cat.No: T79588
Synonym:
Target: VEGFR
Sorafenib tosylate
Cat.No: T0093
Synonym: 甲苯磺酸索拉非尼,Bay 43-9006
Target: Apoptosis, Raf, VEGFR, FLT, Ferroptosis, PDGFR, c-Kit, Autophagy
Ripretinib
Cat.No: T8482
Synonym: DCC-2618,瑞普替尼
Target: Apoptosis, VEGFR, FLT, PDGFR, c-Kit
AST 487
Cat.No: T4053
Synonym: NVP-AST 487
Target: VEGFR, FLT, c-RET, Bcr-Abl, c-Kit
TIE-2/VEGFR-2 kinase-IN-3
Cat.No: T79858
Synonym:
Target:
AG-13958
Cat.No: T7493
Synonym: AG-013958,N-[2-氟-5-[[3-[(1E)-2-(2-吡啶基)乙烯基]-1H-吲唑-6-基]氨基]苯基]-1,3-二甲基-1H-吡唑-5-甲酰胺
Target: VEGFR
VEGFR2-IN-3
Cat.No: T79009
Synonym:
Target: VEGFR
Cabozantinib
Cat.No: T2586
Synonym: 卡博替尼,XL184,BMS-907351
Target: Apoptosis, VEGFR, FLT, c-Met/HGFR, c-RET, TAM Receptor, c-Kit
Sitravatinib
Cat.No: T4349
Synonym: MG516,MGCD516
Target: Discoidin Domain Receptor (DDR), VEGFR, FLT, Trk receptor, TAM Receptor, c-Kit, Ephrin Receptor
PI3K/VEGFR2-IN-1
Cat.No: T72713
Synonym:
Target: PI3K
Dovitinib lactate hydrate
Cat.No: T6479
Synonym: Dovitinib (TKI258) Lactate,多韦替尼,Dovitinib Lactate,TKI258
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
Dovitinib lactate
Cat.No: T7104
Synonym: CHIR-258 lactate,多韦替尼乳酸盐,TKI-258 lactate
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
Dovitinib
Cat.No: T6289
Synonym: TKI258,多韦替尼,CHIR-258,度维替尼
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
Linifanib
Cat.No: T2514
Synonym: 利尼伐尼,ABT-869,RG3635,AL-39324
Target: Apoptosis, c-Fms, VEGFR, FLT, CSF-1R, PDGFR, c-Kit, Autophagy
Cabozantinib hydrochloride
Cat.No: T5164
Synonym: XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351,盐酸卡博替尼
Target: VEGFR, FLT, c-Met/HGFR, TAM Receptor, c-Kit, ROR
PF 477736
Cat.No: T6028
Synonym: PF 00477736,PF-477736,PF-736,PF-00477736,PF477736
Target: c-Fms, VEGFR, FGFR, FLT, c-RET, Chk, CDK, Src, Aurora Kinase
(Rac)-SAR131675
Cat.No: T3691
Synonym: SAR131675
Target: VEGFR
Tivozanib hydrochloride hydrate
Cat.No: T63505
Synonym: AV-951 hydrochloride hydrate,KRN951 hydrochloride hydrate
Target: VEGFR
MAZ51
Cat.No: T8496
Synonym:
Target: Apoptosis, VEGFR
EG00229
Cat.No: T11153
Synonym:
Target: Others
NVP-ACC789
Cat.No: T3463
Synonym: ACC-789,ZK202650
Target: VEGFR, PDGFR
Brivanib
Cat.No: T6036
Synonym: BMS-540215,布立尼布
Target: EGFR, VEGFR, FGFR, Autophagy
Sorafenib-d3
Cat.No: T16909
Synonym: Sorafenib (D3),Bay 43-9006 (D3)
Target: Raf, VEGFR
Motesanib
Cat.No: T2288
Synonym: AMG 706,莫特塞尼,莫替沙尼
Target: VEGFR, c-Kit
Chloropyramine hydrochloride
Cat.No: T0263
Synonym: Nilfan,盐酸氯吡胺,Alergosan,Halopyramine hydrochloride
Target: FAK, VEGFR, Histamine Receptor
CGP60474
Cat.No: T14943
Synonym:
Target: VEGFR, CDK, PKC
Tivozanib
Cat.No: T2456
Synonym: 替沃扎尼,AV-951,KRN951
Target: VEGFR, PDGFR, Ephrin Receptor
Cediranib
Cat.No: T2500
Synonym: AZD2171,NSC-732208,西地尼布
Target: VEGFR, FLT, PDGFR, c-Kit, Autophagy
Pazopanib
Cat.No: T0097L
Synonym: 帕唑帕尼,GW786034
Target: VEGFR, FGFR, PDGFR, c-Kit, Autophagy
OSI-930
Cat.No: T2624
Synonym: OSI 930,噻尔非尼
Target: Apoptosis, c-Fms, Raf, VEGFR, FLT, CSF-1R, Src, c-Kit
Fruquintinib
Cat.No: T2656
Synonym: HMPL-013,呋喹替尼
Target: VEGFR
Vandetanib Fumarate
Cat.No: T1656L
Synonym: HSDB 8198,Zactima,Caprelsa,ZD 6474,Vandetanib
Target:
(S)-3-Hydroxy Midostaurin
Cat.No: T12791
Synonym: (S)-CGP52421
Target: Others
Pegdinetanib
Cat.No: T77148
Synonym:
Target:
N-Desethyl Sunitinib hydrochloride
Cat.No: T74127
Synonym:
Target:
VEGFR-2-IN-32
Cat.No: T79495
Synonym:
Target: VEGFR
Multi-kinase-IN-3
Cat.No: T63870
Synonym:
Target:
N-Desethyl Sunitinib
Cat.No: T12145
Synonym: N-去乙基-舒尼替尼,SU-11662
Target: VEGFR, PDGFR, c-Kit
Cat. No. Product Name Target Signaling Pathways
TN2019 Orobol

3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon,3',4',5,7-四羟基异黄酮

BCL; Caspase; PI3K Apoptosis; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) 是酪氨酸特异性蛋白激酶和磷脂酰肌醇转换的抑制剂。Orobol 抑制 PI3K,对 PI3K α/β/γ/K/δ 的 IC50 为 3.46-5.27 μM。 Orobol 具有抗皮肤老化和抗肥胖的作用。
T13108 Pamufetinib

H2OL3Q4XRD,4-(2-Fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylquinoline-6-carboxamide,TAS-115

VEGFR; c-Met/HGFR Angiogenesis; Tyrosine Kinase/Adaptors
Pamufetinib (TAS-115) 是VEGFR 和c-Met/HGFR 抑制剂,能够抑制 rVEGFR2 (IC50:30 nM)和 rMET (IC50:32 nM)的活性。
T1152 Albendazole

SKF-62979,阿苯达唑

HIF/HIF Prolyl-Hydroxylase; Microtubule Associated; Antibiotic; Parasite Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Microbiology/Virology
Albendazole (SKF-62979) 是一种广谱抗寄生虫剂,具有高效,低宿主毒性的特点。 它用于研究人类和动物的胃肠道寄生虫。

天然产物

Orobol
Cat.No: TN2019
Synonym: 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon,3',4',5,7-四羟基异黄酮
Target: BCL, Caspase, PI3K
Pamufetinib
Cat.No: T13108
Synonym: H2OL3Q4XRD,4-(2-Fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylquinoline-6-carboxamide,TAS-115
Target: VEGFR, c-Met/HGFR
Albendazole
Cat.No: T1152
Synonym: SKF-62979,阿苯达唑
Target: HIF/HIF Prolyl-Hydroxylase, Microtubule Associated, Antibiotic, Parasite
Cat. No. Product Name Species Expression System
TMPY-01936 VEGFR3/FLT4 Protein, Mouse, Recombinant (His)

Flt-4,VEGFR-3,Chy,fms related tyrosine kin...

Mouse HEK293 Cells
VEGFR3/FLT4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is P35917-1.
TMPY-00949 VEGFR3/FLT4 Protein, Human, Recombinant (His)

VEGFR-3,PCL,FLT41,VEGF Receptor 3...

Human HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession number is P35916-1.
TMPY-01937 VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)

VEGFR-3,fms related tyrosine kinase 4,...

Mouse HEK293 Cells
VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 112 kDa and the accession number is P35917-1.
TMPK-00445 VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi)

PCL,PCLFLT41,VEGFR3,FLT-4,LMPH1A,FLT-41,

Human HEK293 Cells
Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly expressed in CRC cells and stromal vessels. VEGF-R1 strong positive staining correlated with shorter survival after CRC surgery. VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 87.4 k...
TMPY-01069 VEGFR3/FLT4 Protein, Human, Recombinant (hFc)

FLT41,fms related tyrosine kinase 4,VEGF Receptor 3...

Human HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 111.3 kDa and the accession number is P35916-1.
TMPY-06620 VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated

PCL,VEGFR-3,LMPH1A,fms related tyrosine ki...

Human HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 87.80 kDa and the accession number is NP_002011.2.
TMPK-00446 VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated

PCL,FLT-41,LMPH1A,FLT-4,VEGFR3,PCLFLT41,

Human HEK293 Cells
Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly expressed in CRC cells and stromal vessels. VEGF-R1 strong positive staining correlated with shorter survival after CRC surgery. VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted m...
TMPY-04794 VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc)

VEGFR,kinase insert domain receptor,Flk-1,VEGFR...

Human HEK293 Cells
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.5 kDa and the accession number is P35968-1.
TMPY-04795 VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His)

kinase insert domain receptor,VEGFR2,FLK1,Flk-1,CD<...

Human HEK293 Cells
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.9 kDa and the accession number is P35968-1.
TMPY-04796 VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)

FLK1,kinase insert domain receptor,CD309,VEGFR<...

Human HEK293 Cells
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.8 kDa and the accession number is P35968-1.
TMPY-04802 VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc)

kinase insert domain receptor,CD309,VEGFR2...

Human HEK293 Cells
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.4 kDa and the accession number is P35968-1.
TMPY-06986 FGF-8b Protein, Human, Recombinant

NEWENTRY,fibroblast growth factor 8 (androgen-induced),FGF-8...

Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-00132 Mesothelin Protein, Human, Recombinant

MPF,SMRP,Mesothelin

Human HEK293 Cells
Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3.
TMPY-04935 CD47 Protein, Human, Recombinant (aa 1-139, His)

MER6,CD47 molecule,IAP,OA3

Human HEK293 Cells
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q08722-3.
TMPY-03763 Neuropilin-2 Protein, Human, Recombinant (hFc)

Neuropilin-2,NPN2,neuropilin 2,PRO2714,VEGF165R2,NP2

Human HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 120.7 kDa and the accession number is O60462-3.
TMPY-05191 CD47 Protein, Human, Recombinant, Biotinylated

CD47 molecule,MER6,OA3,IAP

Human HEK293 Cells
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-04683 CD47 Protein, Human, Recombinant

MER6,CD47 molecule,OA3,IAP

Human HEK293 Cells
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-00072 GITR/TNFRSF18 Protein, Human, Recombinant (His)

AITR,GITR-D,tumor necrosis factor receptor superfamily, memb...

Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3.
TMPY-01897 PRSS3 Protein, Human, Recombinant (His)

PRSS4,TRY4,TRY3,RP11-176F3.3,T9,M...

Human HEK293 Cells
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ...
TMPY-01020 Periostin/OSF-2 Protein, Human, Recombinant (His)

PN,OSF-2,OSF2,periostin,periostin, osteoblast specific facto...

Human HEK293 Cells
Periostin/OSF-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is Q15063-3.
TMPY-00892 Neuropilin-2 Protein, Human, Recombinant (His)

NP2,PRO2714,VEGF165R2,neuropilin 2,NPN2,Neuropilin-2

Human HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is O60462-3.
TMPY-01180 CD86 Protein, Human, Recombinant (His)

CD86 antigen,B70,B7.2,B7-2,CD28LG2,LAB72

Human HEK293 Cells
CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3.
TMPY-05748 CD45 Protein, Human, Recombinant (aa 26-577, His)

L-CA,T200,LCA,B220,protein tyrosine phosphatase, receptor ty...

Human HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3.
TMPY-04142 RANK/TNFRSF11A Protein, Human, Recombinant (hFc)

OPTB7,OFE,OSTS,LOH18CR1,FEO,TRANCER,tumor necrosis factor re...

Human HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9Y6Q6-3.
TMPJ-01099 IL-15RA Protein, Human, Recombinant (hFc, Human Cells)

interleukin-15 receptor subunit α,IL15RA,interleukin-15 rece...

Human HEK293 Cells
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun...
TMPY-04298 CDCP1 Protein, Human, Recombinant (His)

TRASK,CD318,CUB domain containing protein 1,SIMA1

Human HEK293 Cells
CDCP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H5V8-3.
TMPY-00357 HNT/NTM Protein, Human, Recombinant (His)

HNT,NTRI,IGLON2,neurotrimin

Human HEK293 Cells
HNT/NTM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q9P121-3.
TMPY-00480 NCAM1 Protein, Human, Recombinant (His)

neural cell adhesion molecule 1,CD56,MSK39,NCAM

Human HEK293 Cells
NCAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.1 kDa and the accession number is P13591-3.
TMPK-00447 CD45 Protein, Human, Recombinant (aa 26-577, hFc)

CD45,CD45R,LCA,PTPRC,L-CA,T200,B220,GP180,LY5,EC 3....

Human HEK293 Cells
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (aa 26-577...
TMPY-01268 SMYD3 Protein, Human, Recombinant (GST)

SET and MYND domain containing 3,ZMYND1,KMT3

Human Baculovirus Insect Cells
SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger and one SET domain. SMYD3 is a histone H3 lysine-4-specific methyltransferase. It is expressed in skeletal muscles and testis. It is overexpressed in a majority of colorectal carcinoma (CRC) and hepatocellular carcinoma (HCC). SMYD3 plays an important role in transcriptional reg...
TMPY-03621 EphB2 Protein, Mouse, Recombinant (hFc)

Tyro5,Erk,Qek5,ETECK,Hek5,Drt,EPH receptor B2,Nuk,Prkm5,Sek<...

Mouse HEK293 Cells
EphB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.6 kDa and the accession number is P54763-3.
TMPJ-01288 KLF6 Protein, Human, Recombinant

CPBP,GC-Rich Sites-Binding Factor GBF,Suppressor of Tumorige...

Human E. coli
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will resul...
TMPY-04386 EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)

PCBC,CAPB,Hek5,EK5,EPHT3,EPH receptor B2,Tyro5,DRT,...

Human Baculovirus Insect Cells
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.2 kDa and the accession number is P29323-3.
TMPY-03149 CDCP1 Protein, Human, Recombinant (mFc)

TRASK,SIMA135,CD318,CUB domain containing ...

Human HEK293 Cells
CDCP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 61.4 kDa and the accession number is Q9H5V8-3.
TMPK-00401 FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

ECT1,K-SAM,CD332,CEK3,FGFR2 α,CFD...

Human HEK293 Cells
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs.
TMPK-00398 FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)

Fibroblast growth factor receptor 2,CD332,...

Human HEK293 Cells
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
TMPY-04015 COL9A1 Protein, Human, Recombinant (mFc)

DJ149L1.1.2,STL4,collagen, type IX, alpha 1,MED,EDM6,collage...

Human HEK293 Cells
COL9A1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 59.2 kDa and the accession number is P20849-3.
TMPJ-00391 FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)

FGF R2b,KGFR,BFR-1,FGFR2 β,FGFR2b,FGFR2,FGFR2 beta,CD3

Human HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802-3.
TMPY-05514 RANK/TNFRSF11A Protein, Human, Recombinant (mFc)

OFE,RANK,OPTB7,FEO,tumor necrosis factor receptor superfamil...

Human HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q9Y6Q6-3.
TMPY-00276 PLGF/PGF Protein, Human, Recombinant (mFc)

placental growth factor,D12S1900,PLGF,SHGC-10760,PGFL,PlGF-2

Human HEK293 Cells
PLGF/PGF Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.7 kDa and the accession number is P49763-3.
TMPY-06411 GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated

CD357,GITR-D,tumor necrosis factor receptor superfa...

Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.79 kDa and the accession number is Q9Y5U5-3.
TMPY-03960 COL9A1 Protein, Human, Recombinant (His)

EDM6,collagen, type IX, α1,STL4,collagen, type IX, alpha 1,M...

Human HEK293 Cells
COL9A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.2 kDa and the accession number is P20849-3.
TMPY-00715 CD84 Protein, Human, Recombinant (His)

LY9B,mCD84,CD84 molecule,hCD84,SLAMF5

Human HEK293 Cells
CD84 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9UIB8-3.
TMPY-03969 SUSD4 Protein, Human, Recombinant (mFc)

sushi domain containing 4,PRO222

Human HEK293 Cells
SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and testis but not other tissues. In brains, SUSD4 is highly expressed in the white matter on oligodendrocytes/axons, and in eyes, it is exclusively expressed on the photoreceptor outer segments. In in vitro complement assays, SUSD4 augments the alternative but not the classical path...
TMPY-04216 EphB2 Protein, Mouse, Recombinant (His)

Drt,Nuk,Qek5,Tyro5,Prkm5,Sek3,ETECK,Cek5,Hek5,EPH r...

Mouse HEK293 Cells
EphB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is P54763-3.
TMPJ-00465 PTP1C Protein, Human, Recombinant (His)

HCP,Hematopoietic Cell Protein-Tyrosine Phosphatase,SH-PTP1,...

Human E. coli
Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against inter...
TMPY-02573 IL-17RC Protein, Human, Recombinant (aa 1-454, His)

IL17RL,interleukin 17 receptor C,IL17-RL,UNQ6118/PRO20040/PR...

Human Baculovirus Insect Cells
IL-17RC Protein, Human, Recombinant (aa 1-454, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49.6 kDa and the accession number is Q8NAC3-3.
TMPY-03883 CD47 Protein, Human, Recombinant (hFc)

OA3,CD47 molecule,IAP,MER6

Human HEK293 Cells
CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession number is Q08722-3.
TMPY-01656 VEGF183 Protein, Human, Recombinant

血管内皮生长因子,VEGF165,VPF,VEGF,vascular endothelial growth factor...

Human Baculovirus Insect Cells
VEGF183 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 21 kDa and the accession number is P15692-3.
TMPK-00400 FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

Fibroblast growth factor receptor 2,KGFR,FGFR-2,KSAM,CD3...

Human HEK293 Cells
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.3 kDa and the accession number is P21802-3.
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重组蛋白

VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01936
Species: Mouse
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His)
Cat.No: TMPY-00949
Species: Human
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-01937
Species: Mouse
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00445
Species: Human
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01069
Species: Human
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06620
Species: Human
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated
Cat.No: TMPK-00446
Species: Human
Expression System: HEK293 Cells
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc)
Cat.No: TMPY-04794
Species: Human
Expression System: HEK293 Cells
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His)
Cat.No: TMPY-04795
Species: Human
Expression System: HEK293 Cells
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)
Cat.No: TMPY-04796
Species: Human
Expression System: HEK293 Cells
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc)
Cat.No: TMPY-04802
Species: Human
Expression System: HEK293 Cells
FGF-8b Protein, Human, Recombinant
Cat.No: TMPY-06986
Species: Human
Expression System: E. coli
Mesothelin Protein, Human, Recombinant
Cat.No: TMPY-00132
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant (aa 1-139, His)
Cat.No: TMPY-04935
Species: Human
Expression System: HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03763
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant, Biotinylated
Cat.No: TMPY-05191
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant
Cat.No: TMPY-04683
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His)
Cat.No: TMPY-00072
Species: Human
Expression System: HEK293 Cells
PRSS3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01897
Species: Human
Expression System: HEK293 Cells
Periostin/OSF-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01020
Species: Human
Expression System: HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-00892
Species: Human
Expression System: HEK293 Cells
CD86 Protein, Human, Recombinant (His)
Cat.No: TMPY-01180
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His)
Cat.No: TMPY-05748
Species: Human
Expression System: HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04142
Species: Human
Expression System: HEK293 Cells
IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
Cat.No: TMPJ-01099
Species: Human
Expression System: HEK293 Cells
CDCP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04298
Species: Human
Expression System: HEK293 Cells
HNT/NTM Protein, Human, Recombinant (His)
Cat.No: TMPY-00357
Species: Human
Expression System: HEK293 Cells
NCAM1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00480
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, hFc)
Cat.No: TMPK-00447
Species: Human
Expression System: HEK293 Cells
SMYD3 Protein, Human, Recombinant (GST)
Cat.No: TMPY-01268
Species: Human
Expression System: Baculovirus Insect Cells
EphB2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-03621
Species: Mouse
Expression System: HEK293 Cells
KLF6 Protein, Human, Recombinant
Cat.No: TMPJ-01288
Species: Human
Expression System: E. coli
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)
Cat.No: TMPY-04386
Species: Human
Expression System: Baculovirus Insect Cells
CDCP1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-03149
Species: Human
Expression System: HEK293 Cells
FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00401
Species: Human
Expression System: HEK293 Cells
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
Cat.No: TMPK-00398
Species: Human
Expression System: HEK293 Cells
COL9A1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-04015
Species: Human
Expression System: HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
Cat.No: TMPJ-00391
Species: Human
Expression System: HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05514
Species: Human
Expression System: HEK293 Cells
PLGF/PGF Protein, Human, Recombinant (mFc)
Cat.No: TMPY-00276
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06411
Species: Human
Expression System: HEK293 Cells
COL9A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03960
Species: Human
Expression System: HEK293 Cells
CD84 Protein, Human, Recombinant (His)
Cat.No: TMPY-00715
Species: Human
Expression System: HEK293 Cells
SUSD4 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-03969
Species: Human
Expression System: HEK293 Cells
EphB2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04216
Species: Mouse
Expression System: HEK293 Cells
PTP1C Protein, Human, Recombinant (His)
Cat.No: TMPJ-00465
Species: Human
Expression System: E. coli
IL-17RC Protein, Human, Recombinant (aa 1-454, His)
Cat.No: TMPY-02573
Species: Human
Expression System: Baculovirus Insect Cells
CD47 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03883
Species: Human
Expression System: HEK293 Cells
VEGF183 Protein, Human, Recombinant
Cat.No: TMPY-01656
Species: Human
Expression System: Baculovirus Insect Cells
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00400
Species: Human
Expression System: HEK293 Cells
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